ANTI-CANCER POTENTIAL OF TRANSIENTLY TRANSFECTED HER2-SPECIFIC HUMAN MIXED CAR-T AND NK CELL POPULATIONS IN EXPERIMENTAL MODELS: INITIAL STUDIES ON FUCOSYLATED CHONDROITIN SULFATE USAGE FOR SAFER TREATMENT

Human epidermal growth factor receptor 2 (HER2) is overexpressed in numerous cancer cell types.Therapeutic antibodies and chimeric antigen receptors (CARs) against HER2 were developed to treat human tumors.The major limitation of anti-HER2 CAR-T lymphocyte therapy is attributable to the low HER2 expression in a wide range of normal tissues.Thus, si

Abstract Background For heterogeneous tissues, such as blood, measurements of gene expression are confounded by relative proportions of cell types involved.Conclusions have to rely on estimation of gene expression signals for homogeneous cell populations, e.g.by applying micro-dissection, fluorescence activated cell sorting, or in-silico Trousers d

Social networks play an important role in today’s society and in our relationships with others.They give the Internet user the opportunity to play an active role, e.g., one can relay certain information via a blog, a comment, or even a vote.The Internet user has the possibility to share any content at any time.However, some malicious Internet use

Dafna Wajszilber,1 José Arturo Santiseban,1,2 Reut Gruber1,2 1Department of Psychiatry, Faculty of Medicine, McGill Bare End Power Cords University, Montréal, Quebec, Canada; 2Attention Behavior and Sleep Lab, Douglas Research Center, Montréal, Quebec, Canada Abstract: Attention deficit/hyperactivity disorder (ADHD) is one of t